How Severe Are GLP-1 Side Effects?

Tracking the Real-World Impact of GLP-1 Adverse Effects

Date added: December 02, 2025
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← GLP-1 Weight-Loss Drugs (Ozempic, Wegovy, Mounjaro)?

Reported side effects include nausea, vomiting, diarrhea, constipation, loss of lean mass, fatigue, “Ozempic face,” and less commonly, suicidal or self-injurious ideation. This question captures severity—not just presence—of adverse effects.

It also helps identify whether side effects are mild and temporary, or severe enough to disrupt daily life or cause discontinuation.

Choose which option best describes your experience:

The side effects I experienced (or, as a medical professional, the general patient-reported side effects) were:

Option 1: Mild / None
Option 2: Significant / Severe

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